Perioperative Optimization Strategy of Sodium and Albumin in a Sepsis Patient Secondary to Femoral Cellulitis with a History of Epilepsy
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Abstract
Background and Objectives: Sepsis secondary to femoral cellulitis with complex comorbidities requires aggressive perioperative stabilization. This case report aims to analyze the clinical management strategy in a cellulitis patient with severe hyponatremia, hypoalbuminemia, and epilepsy to contribute to the literature on comprehensive management strategies in a referral hospital in Indonesia. Subject and Method: A 44-year-old male (height 168 cm, weight 65 kg) with right femoral cellulitis, sepsis, severe hyponatremia (125 mmol/L), hypoalbuminemia (2.5 g/dL), and active epilepsy was classified as ASA III physical status. Management strategies focused on pre-operative metabolic optimization through sodium correction targeting 140 mmol/L and albumin substitution to 3.5 g/dL to stabilize the seizure threshold and oncotic pressure before debridement. Result: Precise calculation of sodium and albumin deficits, along with the maintenance of anticonvulsant regimens, are key variables in mitigating neurological risks and intraoperative hemodynamic instability. Conclusion: Target-based metabolic optimization through a multidisciplinary approach effectively reduces perioperative morbidity in soft tissue sepsis with neurological comorbidities.
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References
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